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Diplom- und Master-Arbeiten (eigene und betreute):

L. Wagner:
"Reproducibility of the HR-pQCT based FE-Analysis of the Distal Radius";
Betreuer/in(nen): P.K. Zysset; Institut für Leichtbau und Struktur-Biomechanik, TU Wien, 2010; Abschlussprüfung: 08.09.2010.



Kurzfassung englisch:
High Resolution peripheral Quantitative Computed Tomography (HR-pQCT) based Finite Element (FE) analysis of the distal radius has the potential to become a future diagnostic tool for osteoporosis. When pathological processes or therapeutic effects shall be quantified, it is necessary to know the reproducibility of a diagnostic tool.

Six pairs of fresh frozen human cadaver forearms were scanned six times with the HR-pQCT system at the AKH Wien. The first series of the scans was selected as the Baseline (BL) and the following five represent the Follow Ups (FU). Next to the clinical region, currently investigated, (STD region) a second, distally shifted, region (MD region) and a third region, representing a combination of STD and MD (DS region), were analysed. Two modelling strategies, the micro FE (muFE) approach and the homogenized FE (hFE) method, were used to create the FE models of the three radius regions, respectively. In addition to the FE analysis, the bone mineral density (BMD) was evaluated from these HR-pQCT images. Image registration was performed on the five FU to find the corresponding BL images, and the whole analysis (BMD and FE) was repeated for these registered FU.

Erstellt aus der Publikationsdatenbank der Technischen Universität Wien.